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International Journal of Biomedical Engineering Volume 1, Issue 1 Research Article
IJBE
International Journal of Biomedical...
International Journal of Biome...
Date: March 2025
Article: ijbe.2025.0102
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Deep Learning-Assisted Retinal Vessel Segmentation for Diabetic Retinopathy Screening

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Highlights
  • Diabetic retinopathy (DR) affects approximately 100 million people worldwide, with timely screening critical for preventing vision loss.
  • RetinalNet-Lite achieves 98.1% sensitivity and 97.8% specificity for DR screening using a lightweight CNN deployable on mobile devices without cloud connectivity.
  • The architecture employs depthwise separable convolutions and knowledge distillation from a larger teacher network, achieving 94% parameter reduction with <1.5% accuracy penalty.
Abstract
Diabetic retinopathy (DR) affects approximately 100 million people worldwide, with timely screening critical for preventing vision loss. RetinalNet-Lite achieves 98.1% sensitivity and 97.8% specificity for DR screening using a lightweight CNN deployable on mobile devices without cloud connectivity. The architecture employs depthwise separable convolutions and knowledge distillation from a larger teacher network, achieving 94% parameter reduction with <1.5% accuracy penalty. Validated prospectively on 12,000 retinal images across three clinical sites in Nigeria, Ghana, and Kenya, RetinalNet-Lite demonstrates consistent performance across population demographics, camera models, and lighting conditions representative of resource-limited settings.
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